Cannabinoid receptors can be activated by endocannabinoids produced by our body (anandamide and arachidonoylglycerol), synthetic cannabinoids, or cannabinoid herbs found in cannabis. Thus, the body perceives herbal cannabinoids as identical and does not reject them.
We have CB1 receptors in the central nervous system, connective tissue, glands and glands, and in the cerebral cortex and brain regions such as the hippocampus, basal ganglia, cerebellum, and amygdala. However, CB2 receptors are mostly found in lymphatic organs (spleen, esophagus, palate, bone marrow) and white blood cells. Because the receptors are arranged in two different regions, they are activated by other types of cannabinoids.
Thus, THC, which also contains psychoactive agents, acts on the CB1 receptors and thus works well in all depressive states, Alzheimer’s and Parkinson’s, pain, inflammation (arthritis, lupus), hormonal disorders and many cancers. In contrast to THC, CBD acts on the CB2 receptors, helping with all inflammatory bowel diseases, such as Crohn’s disease and leaky gut syndrome, and has many positive effects on all forms of blood disorders and cancer.
Each individual differs in the number of CB1 and CB2 receptors, which depends on their response and sensitivity to CBD and THC. In order to maximize the benefit, the ratio of THC to CBD in preparations should vary with the individual and the number of CB1 and CB2 receptors in his body.
Many researchers believe that CBD is the most important cannabinoid ever discovered, so research and studies continue actively, showing great therapeutic potential in health, and it can even be said to be one of the most popular dietary supplements that individuals consume on a daily basis . Of course, science has already synthesized pure, synthetic cannabinoids, most notably THC and CBD, which it uses to make certain drugs that are already on the market, but experience with synthetic cannabinoids shows that they are significantly less effective than natural forms of cannabinoids.
It is best to look for natural sources of plants, home-controlled production, free of pesticides and herbicides and, if possible, harvested by hand. The quality and characteristics of the products depend largely on the quality of the cannabis. Therefore, the most positive effects of CBD products derived from plants are also relevant to how the plants were grown, where they grew, and how parts of the plant were harvested.